BDBM532581 6-[3-(Difluoromethyl)-4-fluoro-phenyl]-1-[(5-fluoro-3-::US11214563, Example 42

SMILES FC(F)c1cc(ccc1F)-c1cnc2cnn(Cc3cncc(Cl)c3)c2n1

InChI Key InChIKey=FRZCKJSLGGMESU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532581   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532581(US11214563, Example 42 | 6-[3-(Difluoromethyl)-4-f...)
Affinity DataIC50: 79nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent