BDBM532586 1-[(5-Chloro-3-pyridyl)methyl]-6-[3-(difluoromethoxy)-4-fluoro-::US11214563, Example 47

SMILES CN(C)C(=O)Cn1ncc2ncc(nc12)-c1ccc(Cl)cc1F

InChI Key InChIKey=TVIVCHILSPWNAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532586   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532586(US11214563, Example 47 | 1-[(5-Chloro-3-pyridyl)me...)
Affinity DataIC50: 284nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
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Date in BDB:
5/8/2022
Entry Details
US Patent