BDBM532587 2-(6-(4-Chloro-2-fluorophenyl)-1H-pyrazolo[3,4-b]pyrazin-1-yl)-N,N-::US11214563, Example 48

SMILES CN(C)C(=O)Cn1ncc2ncc(nc12)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=LKWUFUPHODNGCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532587   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532587(US11214563, Example 48 | 2-(6-(4-Chloro-2-fluoroph...)
Affinity DataIC50: 2.81E+3nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent