BDBM532590 5-((6-(3-(Difluoromethoxy)-4-fluorophenyl)-1H-pyrazolo[3,4-b]pyrazin-1-::US11214563, Example 51

SMILES COc1cncc(Cn2ncc3ncc(nc23)-c2ccc(F)c(OC(F)F)c2)c1

InChI Key InChIKey=QXNDSWJCOSCVEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532590   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532590(US11214563, Example 51 | 5-((6-(3-(Difluoromethoxy...)
Affinity DataIC50: 3.00E+3nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent