BDBM53262 2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaphthalen-2-yl]sulfanylacetic acid::2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-naphthalen-2-yl]sulfanylethanoic acid::2-[[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxy-2-naphthalenyl]thio]acetic acid::2-[[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxy-2-naphthyl]thio]acetic acid::MLS001196186::SMR000558496::[(4-{[(4-chlorophenyl)sulfonyl]amino}-1-hydroxy-2-naphthyl)thio]acetic acid::cid_1309516

SMILES OC(=O)CSc1cc(NS(=O)(=O)c2ccc(Cl)cc2)c2ccccc2c1O

InChI Key InChIKey=NLRVCTAQYTWYQX-UHFFFAOYSA-N

Data  2 KI  4 IC50  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 53262   

TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-na...)
Affinity DataEC50:  3.68E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-na...)
Affinity DataEC50:  6.30E+3nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetHexokinase HKDC1 [W721R](Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-na...)
Affinity DataIC50: 4.67E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetHexokinase HKDC1 [W721R](Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-na...)
Affinity DataIC50: 1.67E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2011
Entry Details
PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-na...)
Affinity DataIC50: 4.87E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-na...)
Affinity DataIC50: 2.70E+3nMAssay Description:Binding affinity to His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of MCL1-N-terminal b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-na...)
Affinity DataKd:  1.53E+4nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as compound's equilibrium dissociation constant after 60 mins by fluorescence anisotro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-na...)
Affinity DataKi:  820nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-na...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of 1,8-ANS from His6-tagged FABP4 (unknown origin) expressed in Escherichia coli BL21(DE3) cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2017
Entry Details Article
PubMed