BDBM532957 4-(2-Amino-4-pyridyl)-6-(2-chlorophenyl)-1H-pyridin-2-one and N-[4-[2-(2-chlorophenyl)-6-oxo-1H-pyridin-4-yl]-2-pyridyl]-2-methoxy-acetamide::US11219618, Example 11::US11219618, Example 12

SMILES Nc1cc(ccn1)-c1cc([nH]c(=O)c1)-c1ccccc1Cl

InChI Key InChIKey=WEUPTDZSLQUHHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 532957   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM532957(US11219618, Example 12 | 4-(2-Amino-4-pyridyl)-6-(...)
Affinity DataIC50: 7nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM532957(US11219618, Example 12 | 4-(2-Amino-4-pyridyl)-6-(...)
Affinity DataIC50: 45nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent