BDBM532968 N-[4-[2-oxo-6-[4-(trifluoromethyl)-3-thienyl]-1H-pyridin-4-yl]-2-pyridyl]acetamide::US11219618, Example 42

SMILES CC(=O)Nc1cc(ccn1)-c1cc([nH]c(=O)c1)-c1cscc1C(F)(F)F

InChI Key InChIKey=YHZOOIVUJYXALU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532968   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM532968(US11219618, Example 42 | N-[4-[2-oxo-6-[4-(trifluo...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2022
Entry Details
US Patent