BDBM533435 US11220518, Ex. No. E3::US11780853, Example E3

SMILES CCOc1nccc(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C)C[C@@H]2C)C3(C)C)n1

InChI Key InChIKey=TVWXKFDCOKGEPB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 533435   

TargetProtein kinase C beta type Isoform 2(Human)
Pfizer

US Patent
LigandPNGBDBM533435(US11220518, Ex. No. E3 | US11780853, Example E3)
Affinity DataKi:  13.1nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM533435(US11220518, Ex. No. E3 | US11780853, Example E3)
Affinity DataKi:  13.1nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent