BDBM533559 US11225475, Compound 4

SMILES Nc1ccc(nc1NC(=O)N1Cc2cnc(CN3CC(F)C3)cc2C1)-c1ccc(F)cc1F

InChI Key InChIKey=WYLYXYDVSQQWAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 533559   

TargetHistone deacetylase 1(Human)
Alkermes

US Patent
LigandPNGBDBM533559(US11225475, Compound 4)
Affinity DataIC50: 300nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Alkermes

US Patent
LigandPNGBDBM533559(US11225475, Compound 4)
Affinity DataIC50: 2.75E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent