BDBM533574 US11225475, Compound 8

SMILES COCCn1cc2CN(Cc2n1)C(=O)Nc1nc(ccc1N)-c1ccccc1F

InChI Key InChIKey=XLYHHGTWYBVCFI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 533574   

TargetHistone deacetylase 2(Human)
Alkermes

US Patent
LigandPNGBDBM533574(US11225475, Compound 8)
Affinity DataIC50: 2.75E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Alkermes

US Patent
LigandPNGBDBM533574(US11225475, Compound 8)
Affinity DataIC50: 300nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent