BDBM533617 US11225469, Compound 110

SMILES Cc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cc2[N+]([O-])=O)C(F)(F)F)c1

InChI Key InChIKey=BENAHSCGIDYNRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533617   

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandPNGBDBM533617(US11225469, Compound 110)
Affinity DataIC50: 7.50E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent