BDBM534130 4,6-Dimethyl-N-(2'-methyl[1,1'-biphenyl]-2-sulfonyl)-1-benzofuran-2-carboxamide ::WO2022081842, Example 6

SMILES Cc1cc(C)c2cc(oc2c1)C(=O)NS(=O)(=O)c1ccccc1-c1ccccc1C

InChI Key InChIKey=GQMRJESETQQOOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534130   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandPNGBDBM534130(WO2022081842, Example 6 | 4,6-Dimethyl-N-(2'-methy...)
Affinity DataIC50: 128nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandPNGBDBM534130(WO2022081842, Example 6 | 4,6-Dimethyl-N-(2'-methy...)
Affinity DataIC50: 245nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842