BDBM534146 6-Cyclopropyl-4-fluoro-N-(2-methylquinoline-8-sulfonyl)-1-benzofuran-2-carboxamide ::WO2022081842, Example 22

SMILES Cc1ccc2cccc(c2n1)S(=O)(=O)NC(=O)c1cc2c(F)cc(cc2o1)C1CC1

InChI Key InChIKey=LXGMUXSMMQBJTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534146   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandPNGBDBM534146(WO2022081842, Example 22 | 6-Cyclopropyl-4-fluoro-...)
Affinity DataIC50: 9.48nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandPNGBDBM534146(WO2022081842, Example 22 | 6-Cyclopropyl-4-fluoro-...)
Affinity DataIC50: 23nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842