BDBM534173 N-(benzenesulfonyl)-6-cyclopropyl-4-(difluoromethoxy)benzofuran-2-carboxamide::WO2022081842, Example 46::WO2022081842, Example 48

SMILES FC(F)Oc1cc(cc2oc(cc12)C(=O)NS(=O)(=O)c1ccccc1-c1ccccc1)C1CC1

InChI Key InChIKey=CIDAXKMALBNANU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534173   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandPNGBDBM534173(N-(benzenesulfonyl)-6-cyclopropyl-4-(difluorometho...)
Affinity DataIC50: 27nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandPNGBDBM534173(N-(benzenesulfonyl)-6-cyclopropyl-4-(difluorometho...)
Affinity DataIC50: 148nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842