BDBM534811 4-[(1S,4R)-5-(3-methoxyphenyl)- 2,5-diazabicyclo[2.2.1]hept-2-yl]- 2-(1-methyl-1H-pyrazol-4- yl)pyrimidine-5-carbonitrile::US11230547, Compound 1-14

SMILES COc1cccc(c1)N1C[C@@H]2C[C@H]1CN2c1nc(ncc1C#N)-c1cnn(C)c1

InChI Key InChIKey=UFDIHCHYARKTSX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534811   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM534811(4-[(1S,4R)-5-(3-methoxyphenyl)- 2,5-diazabicyclo[2...)Copy SMILESCopy InChI

Affinity DataIC50: 71nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL