BDBM534827 4-[(1S,4R)-5-(3-fluoro-2,2- dimethylpropanoyl)-2,5- diazabicyclo[2.2.1]hept-2-yl]-2-(1- methyl-1H-pyrazol-4- yl)pyrimidine-5-carbonitrile::US11230547, Compound 2-6

SMILES Cn1cc(cn1)-c1ncc(C#N)c(n1)N1C[C@@H]2C[C@H]1CN2C(=O)C(C)(C)CF

InChI Key

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534827   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM534827(4-[(1S,4R)-5-(3-fluoro-2,2- dimethylpropanoyl)-2,5...)Copy SMILES

Affinity DataIC50: 160nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
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