BDBM534850 2-(1-methyl-1H-pyrazol-4-yl)-4-[(3R)- 3-methyl-4-(spiro[2.4]hept-1- ylcarbonyl)piperazin-1-yl]pyrimidine- 5-carbonitrile::US11230547, Compound 4-7

SMILES C[C@@H]1CN(CCN1C(=O)C1CC11CCCC1)c1nc(ncc1C#N)-c1cnn(C)c1

InChI Key InChIKey=NZXMIIYMNBXRAT-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534850   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM534850(2-(1-methyl-1H-pyrazol-4-yl)-4-[(3R)- 3-methyl-4-(...)Copy SMILESCopy InChI

Affinity DataIC50: 87nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
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