BDBM534852 4-[(3R)-3-methyl-4-{[(1S,2R)-2- methylcyclopropyl]carbonyl}piperazin- 1-yl]-2-(1-methyl-1H-pyrazol-4- yl)pyrimidine-5-carbonitrile::US11230547, Compound 4-9

SMILES C[C@@H]1C[C@@H]1C(=O)N1CCN(C[C@H]1C)c1nc(ncc1C#N)-c1cnn(C)c1

InChI Key InChIKey=ZXXHAWWIMOPNIX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534852   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM534852(4-[(3R)-3-methyl-4-{[(1S,2R)-2- methylcyclopropyl]...)Copy SMILESCopy InChI

Affinity DataIC50: 80nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
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