BDBM534855 4-[(3R)-4-(3-cyanophenyl)-3- melhylpiperazin-1-yl]-2-(1-methyl-1H- pyrazol-4-yl)pyrimidine-5-carbonitrile::US11230547, Compound 4-12

SMILES C[C@@H]1CN(CCN1c1cccc(c1)C#N)c1nc(ncc1C#N)-c1cnn(C)c1

InChI Key InChIKey=CCOLVASPQIQNJL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534855   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM534855(4-[(3R)-4-(3-cyanophenyl)-3- melhylpiperazin-1-yl]...)Copy SMILESCopy InChI

Affinity DataIC50: 86nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL