BDBM534857 3-{2-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazin-1-yl]-4-(1- methyl-1H-pyrazol-4- yl)pyrimidin-5-yl}prop-2-yn- 1-ol::US11230547, Compound 5-1

SMILES C[C@@H]1CN(CCN1C(=O)C1CC1)c1ncc(C#CCO)c(n1)-c1cnn(C)c1

InChI Key InChIKey=YMSOLNJKNCHCJJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534857   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM534857(3-{2-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiper...)Copy SMILESCopy InChI

Affinity DataIC50: 19nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
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