BDBM534866 2-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazin-1-yl]-5-(3- methylbut-1-yn-1-yl)-4-(1- methyl-1H-pyrazol-4- yl)pyrimidine::US11230547, Compound 5-8

SMILES CC(C)C#Cc1cnc(nc1-c1cnn(C)c1)N1CCN([C@H](C)C1)C(=O)C1CC1

InChI Key InChIKey=CFXGKGIJYSHOHZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534866   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM534866(2-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazi...)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
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