BDBM534873 1-{5-cyano-6-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazin-1-yl]-2-(1- methyl-1H-pyrazol-4- yl)pyrimidin-4-yl}-3-(1- methylethyl)urea::US11230547, Compound 6-2

SMILES CC(C)NC(=O)Nc1nc(nc(N2CCN([C@H](C)C2)C(=O)C2CC2)c1C#N)-c1cnn(C)c1

InChI Key InChIKey=RHKRTAPIHLGMJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534873   

LigandPNGBDBM534873(1-{5-cyano-6-[(3R)-4- (cyclopropylcarbonyl)-3- met...)
Affinity DataIC50: 5.60nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
US Patent