BDBM534888 1-{5-cyano-6-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazin-1-yl]-2-(1- methyl-1H-pyrazol-4- yl)pyrimidin-4-yl}-3-(2,2,2- trifluoroethyl)urea::US11230547, Compound 6-16

SMILES C[C@@H]1CN(CCN1C(=O)C1CC1)c1nc(nc(NC(=O)NCC(F)(F)F)c1C#N)-c1cnn(C)c1

InChI Key InChIKey=RXTNIPLYBDOOAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534888   

LigandPNGBDBM534888(1-{5-cyano-6-[(3R)-4- (cyclopropylcarbonyl)-3- met...)
Affinity DataIC50: 16nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2022
Entry Details
US Patent