BDBM534890 4-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazin-1-yl]-2-(1- methyl-1H-pyrazol-4-yl)-6- [(oxetan-3- ylmethyl)amino]pyrimidine-5- carbonitrile::US11230547, Compound 6-18

SMILES C[C@@H]1CN(CCN1C(=O)C1CC1)c1nc(nc(NCC2COC2)c1C#N)-c1cnn(C)c1

InChI Key InChIKey=CDSJFZBLNMUBKP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534890   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM534890(4-[(3R)-4- (cyclopropylcarbonyl)-3- methylpiperazi...)Copy SMILESCopy InChI

Affinity DataIC50: 49nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
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