BDBM535128 US11236068, Example 7

SMILES Fc1c(c(Cl)cc2c(ncnc12)N1CCN(CC1)C(=O)C=C)-c1nccc2ccccc12

InChI Key InChIKey=FSXMGQIAYWKYTM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535128   

TargetGTPase KRas [G12C](Human)
Genentech

US Patent
LigandPNGBDBM535128(US11236068, Example 7)
Affinity DataIC50: 17nMAssay Description:To determine the potency of compounds for inhibiting nucleotide exchange, various concentrations were incubated with K-Ras G12C (25 nM in reaction, 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent