BDBM535860 N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morpholinonicotinamide::US11241428, Example 5

SMILES Nc1ccc(nc1NC(=O)c1ccc(nc1)N1CCOCC1)-c1ccc(F)cc1

InChI Key InChIKey=GFIVYKYFGAHRTQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 535860   

TargetHistone deacetylase 1(Human)
Medibiofarma

US Patent
LigandPNGBDBM535860(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morph...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535860(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morph...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
US Patent

TargetPolyamine deacetylase HDAC10(Human)
Medibiofarma

US Patent
LigandPNGBDBM535860(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morph...)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Medibiofarma

US Patent
LigandPNGBDBM535860(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Medibiofarma

US Patent
LigandPNGBDBM535860(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
US Patent