BDBM536333 6-((4'-(1,1,1,3,3,3-hexafluoro-2- hydroxypropan-2-yl)-2-isopropyl-2'- methyl-[1,1'-biphenyl]-4-yl)methyl)- 2-thia-6-azaspiro[3.4]octane 2,2- dioxide::US11242350, Example 11

SMILES CC(C)c1cc(CN2CCC3(CS(=O)(=O)C3)C2)ccc1-c1ccc(cc1C)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=JFPSMMCEDMDRTK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536333   

TargetNuclear receptor ROR-gamma(Human)
Escalier Biosciences

US Patent
LigandPNGBDBM536333(6-((4'-(1,1,1,3,3,3-hexafluoro-2- hydroxypropan-2-...)
Affinity DataIC50: 50nMAssay Description:Compounds of the present invention were tested in a human RORγ ligand binding assay using a commercially available cell based ligand binding rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent