BDBM536387 7-((2-ethyl-4'-(1,1,1,3,3,3- hexafluoro-2-hydroxypropan-2-yl)- [1,1'-biphenyl]-4-yl)methyl)-2-thia- 7-azaspiro[4.4]nonane 2,2-dioxide::US11242350, Example 58

SMILES CCc1cc(CN2CCC3(CCS(=O)(=O)C3)C2)ccc1-c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=TTXLFURLTFPJBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536387   

TargetNuclear receptor ROR-gamma(Human)
Escalier Biosciences

US Patent
LigandPNGBDBM536387(7-((2-ethyl-4'-(1,1,1,3,3,3- hexafluoro-2-hydroxyp...)
Affinity DataIC50: 50nMAssay Description:Compounds of the present invention were tested in a human RORγ ligand binding assay using a commercially available cell based ligand binding rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent