BDBM536761 US11247985, Table 3.65::US11247985, Table 3.78

SMILES CC(C)N1CCC(CC1)NC1CCN(CC1)c1cccc(c1)-c1cc2cc(ccc2[nH]1)C#N

InChI Key InChIKey=VVYWBWFUGQYKCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536761   

TargetTransitional endoplasmic reticulum ATPase(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM536761(US11247985, Table 3.78 | US11247985, Table 3.65)
Affinity DataIC50: 47nMAssay Description:To optimize p97 inhibitors, the C-5 trifluoromethylated trifluoromethylated indole 12 was generated as a promising lead structure. In the ADP-Glo ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetTransitional endoplasmic reticulum ATPase(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM536761(US11247985, Table 3.78 | US11247985, Table 3.65)
Affinity DataIC50: 4.90E+3nMAssay Description:To optimize p97 inhibitors, the C-5 trifluoromethylated trifluoromethylated indole 12 was generated as a promising lead structure. In the ADP-Glo ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent