BDBM536871 N-methyl-3-(3-(2-methylthiazol-5-yl)isoquinolin-8-yl)-1-(1-oxidotetrahydro-2H-thiopyran-4-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxamide::US11247989, Example 45

SMILES CNC(=O)N1CCc2c(C1)c(nn2C1CCS(=O)CC1)-c1cccc2cc(ncc12)-c1cnc(C)s1

InChI Key InChIKey=ZHCWBVCTJXADOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536871   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM536871(N-methyl-3-(3-(2-methylthiazol-5-yl)isoquinolin-8-...)
Affinity DataIC50: 1.54nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
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Date in BDB:
6/13/2022
Entry Details
US Patent