BDBM536878 1-(3-(3-(1-methyl-1H-pyrazol-4-yl)isoquinolin-8-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrrolo[3,2-c]pyridin-5-yl)ethan-1-one::US11247989, Example 53

SMILES CC(=O)N1CCc2c(C1)c(cn2C1CCOCC1)-c1cccc2cc(ncc12)-c1cnn(C)c1

InChI Key InChIKey=SRNHIKMFWZGWNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536878   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM536878(1-(3-(3-(1-methyl-1H-pyrazol-4-yl)isoquinolin-8-yl...)
Affinity DataIC50: 2.38nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
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Date in BDB:
6/13/2022
Entry Details
US Patent