BDBM537179 US11247989, Example 159

SMILES COc1ccc(cc1)C1=NC2C=CC=C(C2O1)c1nn(C2CCOCC2)c2CCN(Cc12)C(C)=O

InChI Key InChIKey=ZWZZAXGJELWCRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 537179   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM537179(US11247989, Example 159)
Affinity DataIC50: 4.11nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent