BDBM537414 (2S,3S)-1-(4-(6- (ethylamino)-1-((1s,4R)-4- ((3-fluoro-4- (trifluoromethyl)pyridin-2- yl)oxy)cyclohexyl)-1H- pyrazolo[4,3-c]pyridin-3- yl)-1H-pyrazol-1- yl)butane-2,3-diol::US11247990, Example 239

SMILES CCNc1cc2n(nc(-c3cnn(C[C@H](O)[C@H](C)O)c3)c2cn1)C1CC[C@@H](CC1)Oc1nccc(c1F)C(F)(F)F

InChI Key InChIKey=XVRJDEANURQYCS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 537414   

TargetTyrosine-protein kinase receptor TYRO3(Human)
Array Biopharma

US Patent
LigandPNGBDBM537414(US11247990, Example 239 | (2S,3S)-1-(4-(6- (ethyla...)
Affinity DataIC50: 20nMAssay Description:TYRO3: Compounds of Formula I were screened for their ability to inhibit TYRO3 kinase using Invitrogen's LanthaScreen Eu Kinase Binding technolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Array Biopharma

US Patent
LigandPNGBDBM537414(US11247990, Example 239 | (2S,3S)-1-(4-(6- (ethyla...)
Affinity DataIC50: 20nMAssay Description:MER: Compounds of Formula I were screened for their ability to inhibit MER kinase using Invitrogen's LanthaScreen Eu Kinase Binding technology. H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Array Biopharma

US Patent
LigandPNGBDBM537414(US11247990, Example 239 | (2S,3S)-1-(4-(6- (ethyla...)
Affinity DataIC50: 20nMAssay Description:AXL: Compounds of Formula I were screened for their ability to inhibit AXL kinase using Invitrogen's LanthaScreen Eu Kinase Binding technology. H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent