BDBM537454 N-ethyl-3-(1-methyl-1H- pyrazol-4-yl)-1-((1s,4s)-4- ((1-methyl-3- (trifluoromethyl)-1H- pyrazol-4- yl)oxy)cyclohexyl)-1H- pyrazolo[4,3-c]pyridin-6- amine::US11247990, Example 279

SMILES CCNc1cc2n(nc(-c3cnn(C)c3)c2cn1)C1CC[C@@H](CC1)Oc1cn(C)nc1C(F)(F)F

InChI Key InChIKey=SBIMUCMFINMYHJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 537454   

TargetTyrosine-protein kinase Mer(Human)
Array Biopharma

US Patent
LigandPNGBDBM537454(US11247990, Example 279 | N-ethyl-3-(1-methyl-1H- ...)
Affinity DataIC50: 20nMAssay Description:MER: Compounds of Formula I were screened for their ability to inhibit MER kinase using Invitrogen's LanthaScreen Eu Kinase Binding technology. H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Array Biopharma

US Patent
LigandPNGBDBM537454(US11247990, Example 279 | N-ethyl-3-(1-methyl-1H- ...)
Affinity DataIC50: 20nMAssay Description:AXL: Compounds of Formula I were screened for their ability to inhibit AXL kinase using Invitrogen's LanthaScreen Eu Kinase Binding technology. H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
Array Biopharma

US Patent
LigandPNGBDBM537454(US11247990, Example 279 | N-ethyl-3-(1-methyl-1H- ...)
Affinity DataIC50: 20nMAssay Description:TYRO3: Compounds of Formula I were screened for their ability to inhibit TYRO3 kinase using Invitrogen's LanthaScreen Eu Kinase Binding technolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent