BDBM538511 US11254663, Example 438

SMILES CC(C)(C)c1nc(no1)C12CCC(CN(C(=O)C34CC(F)(C3)C4)c3cccc(c3)-c3ccc(NS(C)(=O)=O)cc3)(CC1)CC2

InChI Key InChIKey=VSGNUXCDGVPLSD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 538511   

TargetBile acid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM538511(US11254663, Example 438)
Affinity DataEC50:  46nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2022
Entry Details
US Patent