BDBM539181 (R)-4-(1-(4-(dimethylamino)phenyl)-3-(3- (methylamino)piperidine-1-carbonyl)- 1H-pyrazole-5-yl)benzonitrile::US11254676, Example 51

SMILES CN[C@@H]1CCCN(C1)C(=O)c1cc(-c2ccc(cc2)C#N)n(n1)-c1ccc(cc1)N(C)C

InChI Key InChIKey=KIAGQXPGPCRXHP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539181   

TargetLysine-specific histone demethylase 1A(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM539181((R)-4-(1-(4-(dimethylamino)phenyl)-3-(3- (methylam...)
Affinity DataIC50: 35nMAssay Description:The biochemical inhibition activity of the synthesized compounds on LSD1 was measured. The activity measurement was performed using LSD1 fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent