BDBM539549 US11254686, Compound Z332

SMILES C[C@H](Nc1nc(C(=O)NC2CC[C@@H](O)C2)c2sccc2n1)c1ccccn1

InChI Key InChIKey=YJKYOVAWMNRRSS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 539549   

TargetAdenosine receptor A2b(Human)
Corvus Pharmaceuticals

US Patent
LigandPNGBDBM539549(US11254686, Compound Z332)
Affinity DataIC50: 10nMAssay Description:Compounds (Adenosine Receptor modulators) and activity assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Corvus Pharmaceuticals

US Patent
LigandPNGBDBM539549(US11254686, Compound Z332)
Affinity DataIC50: 300nMAssay Description:Compounds (Adenosine Receptor modulators) and activity assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Corvus Pharmaceuticals

US Patent
LigandPNGBDBM539549(US11254686, Compound Z332)
Affinity DataIC50: 500nMAssay Description:Compounds (Adenosine Receptor modulators) and activity assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent

TargetAdenosine receptor A3(Human)
Corvus Pharmaceuticals

US Patent
LigandPNGBDBM539549(US11254686, Compound Z332)
Affinity DataIC50: 500nMAssay Description:Compounds (Adenosine Receptor modulators) and activity assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent