BDBM539880 4-cyano-2- (trifluoro- methyl)benzene-1- sulfonyl chloride::US11260049, Ex. 18

SMILES FC(F)(F)c1cc(ccc1S(Cl)(=O)=O)C#N

InChI Key InChIKey=DMRMWUNIFCEILQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539880   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline Intellectual Property (No. 2)

US Patent
LigandPNGBDBM539880(4-cyano-2- (trifluoro- methyl)benzene-1- sulfonyl ...)
Affinity DataIC50: 55nMAssay Description:TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent