BDBM541359 US11267803, Example 7

SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2c1)C(=O)NC1(CCCCC1)B(O)O

InChI Key InChIKey=JZLLBCKJHDQBDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 541359   

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM541359(US11267803, Example 7)
Affinity DataIC50: 138nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent