BDBM541390 US11267803, Example 38

SMILES CC(C)(O)c1cnnn1[C@H]1C[C@H](N(C1)C(=O)C(C)(CC1CCCCC1)NC(=O)c1ccc(cc1)S(C)(=O)=O)C(=O)NC1(CCCCC1)C(=O)C(N)=O

InChI Key InChIKey=BXRCEXHGYYJDMG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 541390   

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandPNGBDBM541390(US11267803, Example 38)
Affinity DataIC50: 523nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent