BDBM541749 US11267815, Example 2

SMILES CNc1cc2c(cn1)cc(-c1c(F)c(OC)cc(OC)c1F)c1nc(CCCN3CCN(CC3)C(=O)C=C)cn21

InChI Key InChIKey=NZLJJMJCSBHTPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 541749   

TargetFibroblast growth factor receptor 1(Human)
Shanghai Ringene Biopharma

US Patent
LigandPNGBDBM541749(US11267815, Example 2)
Affinity DataIC50: 20nMAssay Description:(1) Preparation of 1×Kinase buffer; (2) Preparation of the gradient concentrations of the compounds: the concentration of the compounds to be tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Shanghai Ringene Biopharma

US Patent
LigandPNGBDBM541749(US11267815, Example 2)
Affinity DataIC50: 20nMAssay Description:(1) Preparation of 1×Kinase buffer; (2) Preparation of the gradient concentrations of the compounds: the concentration of the compounds to be tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent