BDBM541760 US11267815, Example 13

SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1cc2cnc(NCCC#N)nc2n2cc(CCCN3CCN(CC3)C(=O)C=C)nc12

InChI Key InChIKey=KPIOHWQTFQYKKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 541760   

TargetFibroblast growth factor receptor 1(Human)
Shanghai Ringene Biopharma

US Patent
LigandPNGBDBM541760(US11267815, Example 13)
Affinity DataIC50: 20nMAssay Description:(1) Preparation of 1×Kinase buffer; (2) Preparation of the gradient concentrations of the compounds: the concentration of the compounds to be tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Shanghai Ringene Biopharma

US Patent
LigandPNGBDBM541760(US11267815, Example 13)
Affinity DataIC50: 20nMAssay Description:(1) Preparation of 1×Kinase buffer; (2) Preparation of the gradient concentrations of the compounds: the concentration of the compounds to be tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent