BDBM541761 US11267815, Example 14

SMILES CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c3nc(CCCN4CCN(C(=O)C=C)C(C)(C)C4)cn3c2n1

InChI Key InChIKey=XVDHCTBTPGSONC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 541761   

TargetFibroblast growth factor receptor 1(Human)
Shanghai Ringene Biopharma

US Patent
LigandPNGBDBM541761(US11267815, Example 14)
Affinity DataIC50: 20nMAssay Description:(1) Preparation of 1×Kinase buffer; (2) Preparation of the gradient concentrations of the compounds: the concentration of the compounds to be tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Shanghai Ringene Biopharma

US Patent
LigandPNGBDBM541761(US11267815, Example 14)
Affinity DataIC50: 110nMAssay Description:(1) Preparation of 1×Kinase buffer; (2) Preparation of the gradient concentrations of the compounds: the concentration of the compounds to be tested ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent