BDBM542021 US11273153, Compound 5.20

SMILES Nc1nc(F)c(F)c(-c2cc(c(s2)-c2ccc(F)cc2)-c2ccncc2)c1F

InChI Key InChIKey=VAAXPBLDBSJENE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 542021   

TargetMitogen-activated protein kinase 14(Human)
Everbrilliant Pharma

US Patent
LigandPNGBDBM542021(US11273153, Compound 5.20)
Affinity DataKi:  210nMAssay Description:FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Everbrilliant Pharma

US Patent
LigandPNGBDBM542021(US11273153, Compound 5.20)
Affinity DataKi:  210nMAssay Description:FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Everbrilliant Pharma

US Patent
LigandPNGBDBM542021(US11273153, Compound 5.20)
Affinity DataKi:  660nMAssay Description:FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Everbrilliant Pharma

US Patent
LigandPNGBDBM542021(US11273153, Compound 5.20)
Affinity DataKi:  660nMAssay Description:FP signals were measured with a PHERAstar microplate reader (BMG Labtech) using black, low-binding half-area 96 well plates (Corning). Each binding d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent