BDBM542113 US11274090, Example 20 Isomer 2::US11274090, Example 20 Isomer 4

SMILES C[C@@H](CN[C@H](C(=O)Nc1ccc(cn1)-c1cnn(c1)C(F)F)c1ccccc1)c1ccc(cc1)C#N

InChI Key InChIKey=KUVQLANAPSTSND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 542113   

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542113(US11274090, Example 20 Isomer 4 | US11274090, Exam...)
Affinity DataIC50: 13.7nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542113(US11274090, Example 20 Isomer 4 | US11274090, Exam...)
Affinity DataIC50: 2.00E+3nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent