BDBM542429 US11274090, Example 149 Isomer 2::US11274090, Example 149 Isomer 4

SMILES Cn1cc(cn1)-c1ccc(NC(=O)[C@H](NCC(c2ccc(cc2)C#N)C(F)(F)F)c2ccccc2)nc1

InChI Key InChIKey=OOKDMDYSGMQNGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 542429   

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542429(US11274090, Example 149 Isomer 4 | US11274090, Exa...)
Affinity DataIC50: 19nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM542429(US11274090, Example 149 Isomer 4 | US11274090, Exa...)
Affinity DataIC50: 2.00E+3nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent