BDBM542801 3-(((2R,3S)-8-methoxy-2-(6-methoxypyridin-3-yl)-3-methyl-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-3H-imidazo[4,5-b]pyridine::3-(((2S,3R)-8-methoxy-2-(6-methoxypyridin-3-yl)-3- 3H-imidazo[4,5-b]pyridine::US11274108, Example 1-92-enant-C::US11530216, Compound Table B.6

SMILES COc1ccc(cn1)[C@@H]1Oc2c(OC)cc(Cn3cnc4cccnc34)cc2O[C@H]1C

InChI Key InChIKey=YFGSYVYVMKBGBK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 542801   

LigandPNGBDBM542801(3-(((2R,3S)-8-methoxy-2-(6-methoxypyridin-3-yl)-3-...)
Affinity DataIC50: 9nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Gibco LifeTechnologies, BD Biosciences, Perkin Elmer, R&D Systems, Cell Signaling, Thermo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM542801(3-(((2R,3S)-8-methoxy-2-(6-methoxypyridin-3-yl)-3-...)
Affinity DataIC50: 11nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Gibco LifeTechnologies, BD Biosciences, Perkin Elmer, R&D Systems, Cell Signaling, Thermo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM542801(3-(((2R,3S)-8-methoxy-2-(6-methoxypyridin-3-yl)-3-...)
Affinity DataIC50: 12nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Gibco LifeTechnologies, BD Biosciences, Perkin Elmer, R&D Systems, Cell Signaling, Thermo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM542801(3-(((2R,3S)-8-methoxy-2-(6-methoxypyridin-3-yl)-3-...)
Affinity DataIC50: 18nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Gibco LifeTechnologies, BD Biosciences, Perkin Elmer, R&D Systems, Cell Signaling, Thermo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent

LigandPNGBDBM542801(3-(((2R,3S)-8-methoxy-2-(6-methoxypyridin-3-yl)-3-...)
Affinity DataIC50: 840nMAssay Description:All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2022
Entry Details
US Patent