BDBM542987 (+)-(R)-2-(2′,5′-Difluoro-[1,1′-biphenyl]-4-yl)-N-methyl-N-(4-methyl-5-(S-methylsulfonimidoyl)thiazol-2-yl)acetamide::US11278534, Example 7(+)

SMILES CN(C(=O)Cc1ccc(cc1)-c1cc(F)ccc1F)c1nc(C)c(s1)[S@](C)(=N)=O

InChI Key InChIKey=JDZTWDISDHLKCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542987   

TargetCarbonic anhydrase 2(Human)
Innovative Molecules Gmbg

US Patent
LigandPNGBDBM542987((+)-(R)-2-(2′,5′-Difluoro-[1,1′-...)
Affinity DataIC50: 1.00E+4nMAssay Description:A protocol for determination of the carbonic anhydrase enzymatic activity at rt using the pH indicator method is described below:1 μL inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent