BDBM543465 US11279699, Compound Example 16

SMILES CS(=O)(=O)C1CN(Cc2c(F)cc(cc2F)-c2cccn3nc(NC(=O)C4CC4)nc23)C1

InChI Key InChIKey=TUELRWZLSBELGS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 543465   

TargetTyrosine-protein kinase JAK1(Human)
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543465(US11279699, Compound Example 16)
Affinity DataIC50: 50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543465(US11279699, Compound Example 16)
Affinity DataIC50: 50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543465(US11279699, Compound Example 16)
Affinity DataIC50: 50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent