BDBM543954 US11279719, Example Literature Compound 1 (mixture of E/Z isomers) Positive control

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-n1cc(-[#6]-[#6](P([#8])([#8])=O)P([#8])([#8])=O)nn1

InChI Key InChIKey=HPUHKNBKZOAEQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 543954   

TargetGeranylgeranyl pyrophosphate synthase(Human)
Royal Institution For The Advancement of Learning

US Patent
LigandPNGBDBM543954(US11279719, Example Literature Compound 1 (mixture...)
Affinity DataIC50: 100nMAssay Description:The assay was based on a literature procedure (Kavanagh, et al. J. Biol. Chem., 2006, 281, 22004-22012) with minor modifications. All assays were run...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent